New Tests

The unique setup of RaPaed-AIDA-TB allows the evaluation of multiple new test candidates and testing approaches:

Testing Strategies

• Pathogen detection
    ·  Evaluation of the Xpert MTBRIF Ultra® cartridges on different specimen types
    ·  Lipoarabinomannan (LAM) detection in different specimen

• Host immune response
   ·  Assessment of the T cell specific immune response:
    “T cell activation marker TB"

• Host biomarker signatures
   ·  Protein based
   ·  RNA signatures

Furthermore, the project will contribute significantly to the establishment of a biorepository to facilitate future new test evaluation on stored paediatric samples.