New Tests
The unique setup of RaPaed-AIDA-TB allows the evaluation of multiple new test candidates and testing approaches:
Testing Strategies
- Pathogen detection
· Evaluation of the Xpert MTBRIF Ultra® cartridges on different specimen types
· Lipoarabinomannan (LAM) detection in different specimen Host immune response
· Assessment of the T cell specific immune response:
“T cell activation marker TB"Host biomarker signatures
· Protein based
· RNA signatures
![Image ohne Titel](https://cdn.lmu-klinikum.de/309294dae7d6e6e2/9f400e62de09/v/f455650babe3/RaPaed-tb-children-aid-centre-germany19.jpg)
![Image ohne Titel](https://cdn.lmu-klinikum.de/74863897b49d6ab5/107ad3cb66c9/v/dea1d17db06b/RaPaed-tb-children-aid-centre-germany17.jpg)
Furthermore, the project will contribute significantly to the establishment of a biorepository to facilitate future new test evaluation on stored paediatric samples.